Avian malaria and inmune system: the role of MHC

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Published: Jun 23, 2020
DOI: https://doi.org/10.7818/ECOS.1976
Keywords:
Plasmodium, Haemoproteus, Leucocytozoon, Haemosporida, major histocompatibility complex

Main Article Content

Juan Rivero de Aguilar
<p>Instituto de Ecología y Biodiversidad</p> <p>Departamento de Ecología, Facultad de Ciencias</p> <p>Universidad de Chile</p> <p>Las Palmeras 3425, Santiago, Chile.</p>
Lucas Hussing
<p>Instituto de Ecología y Biodiversidad</p> <p>Departamento de Ecología, Facultad de Ciencias</p> <p>Universidad de Chile</p> <p>Las Palmeras 3425, Santiago, Chile</p>

Abstract

Rivero de Aguilar J., Hussing, L. 2020. Avian malaria and inmune system: the role of MHC. Ecosistemas 29(2):1976. https://doi.org/10.7818/ECOS.1976


Avian malaria is a disease caused by mosquito-borne blood parasites. In the host, parasites infect organs and tissues causing cellular damage, thus affecting body condition and survival. The development of the disease is characterized by an initial acute phase, which decrease by the action of the immune response. Major Histocompatibility Complex (MHC) genes encode for MHC molecules, central proteins involved in the adaptive immune response because its role in the activation of B and T cells. Due to this fundamental function, MHC has been the subject of studies in birds the last decades, highlighting the importance of this genetic region in resistance and susceptibility to avian malaria. In this review we present the main results of the work carried out in the study of avian malaria and MHC, specially in the ecological context.

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How to Cite
Rivero de Aguilar, J., & Hussing, L. (2020). Avian malaria and inmune system: the role of MHC. Ecosistemas, 29(2), 1976. https://doi.org/10.7818/ECOS.1976
Issue
Vol. 29 No. 2 (2020): Ecología de transmisión de enfermedades
Section
Review articles
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Author Biographies

Juan Rivero de Aguilar, <p>Instituto de Ecología y Biodiversidad</p> <p>Departamento de Ecología, Facultad de Ciencias</p> <p>Universidad de Chile</p> <p>Las Palmeras 3425, Santiago, Chile.</p>

Postdoc researcher

Lucas Hussing, <p>Instituto de Ecología y Biodiversidad</p> <p>Departamento de Ecología, Facultad de Ciencias</p> <p>Universidad de Chile</p> <p>Las Palmeras 3425, Santiago, Chile</p>

Instituto de Ecología y Biodiversidad (IEB). Estación de Campo Parque Omora, Teniente Muñoz 166, Puerto Williams. Chile.